Targeted Antigen Delivery to DEC-205+Dendritic Cells for Tolerogenic Vaccination
نویسندگان
چکیده
منابع مشابه
Aptamer-targeted Antigen Delivery
Effective therapeutic vaccines often require activation of T cell-mediated immunity. Robust T cell activation, including CD8 T cell responses, can be achieved using antibodies or antibody fragments to direct antigens of interest to professional antigen presenting cells. This approach represents an important advance in enhancing vaccine efficacy. Nucleic acid aptamers present a promising alterna...
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ژورنال
عنوان ژورنال: The Review of Diabetic Studies
سال: 2012
ISSN: 1613-6071,1614-0575
DOI: 10.1900/rds.2012.9.305